Final Program – NEWroscience 2023

International Symposium NEWroscience 2023

Epilepsy & Neuropsychiatric Comorbidities

From Semiology to Neuroplasticity of Vulnerable/Resilient Networks, to Personalized Therapies.

Organizing Institution: Ribeirão Preto School of Medicine – University of São Paulo Ribeirão Preto, São Paulo – Brasil.

Venue: Main Auditorium of the Ribeirão Preto Law School University of São Paulo

NEWroscience 2023

Final Program

Our Scientific Program has Round Tables, Brainstorms and Final Statements, to discuss Philosophical, Scientific and Technological Challenges for Epilepsy Research and Psychiatric Comorbidities.

19th SEPTEMBER

7:15 PM to 8:00 PM

OPENING CEREMONY AND KEYNOTE SPEECH

Norberto Garcia-Cairasco - Physiology Department. Ribeirão Preto Medical School. University of São Paulo. <ngcairas@usp.br>

Promoting Paradigm Shifts in Epileptology over four decades. The Neurophysiology and Experimental Neuroethology Laboratory (LNNE) Historical Contributions in Brazil, Latin America, and the World

8:00PM to 10:00PM

WELCOME COCKTAIL

20th SEPTEMBER

8:15AM to 12:15AM

FIRST ROUND TABLE: MORNING SESSION

What can we learn from the Combination of Orthodox Scientific and Ancestral Epistemologies, Multiple Knowledges, as applied to Epilepsy and Neuropsychiatric Comorbidities?

Chair: Norberto Garcia-Cairasco;
Co-Chair: Sandra Orozco.

8:15AM to 8:45AM

Dinesh Upadhya - Department of Anatomy, Kasturba Medical College, Manipal India. Joining Ayurvedic Medicine and Contemporary Neuroscience in Epileptology Research. <dineshupadhya@gmail.com>

8:45AM to 9:15AM

Symon Kariuki. KEMRI/Wellcome Trust Research Program: Kilifi, Kenia, Africa. Integrating Traditional and Complementary Medicine in the Treatment of Epilepsies and Comorbidities. African Challenges and Reflections. <skariuki@kemri-wellcome.org>

9:15AM to 9:45AM

Elizabeth Dogbey. School of Pharmacy, Department of Pharmacology and Toxicology, University of Ghana, Accra, Ghana, Africa. Integrating Traditional Healers Knowledge and Ethnopharmacology with Contemporary Neurology in the Epilepsies. <knoxemaliz2002@yahoo.com>

9:45AM to 10:15AM

COFFEE-BREAK

10:15AM to 10:45AM

Bruno Benitez. Harvard Medical School - Beth Israel Deaconess Medical Center Broad Institute - MIT & Harvard. Boston, USA. A Multi-omic Approach Applied to Alzheimer's Disease and Epilepsy. <bbenitez@bidmc.harvard.edu>

10:45AM to 11:15M

Sergio Nojiri. Ribeirão Preto Law School. University of São Paulo, Brasil. Neuroscience, Law and the Epilepsies. <nojiri@usp.br>

11:15AM to 12:15AM

GENERAL DISCUSSION

12:15AM to 2:00PM

LUNCH-BREAK

2:00PM to 6:00PM

SECOND ROUND TABLE: AFTERNOON SESSION

From Bench to Bedside: New Techniques for Analyzing Behavior and Correlated Brain Activity.

Chair: Maria Elisa Calcagnotto;
Co-Chair: Patrick Forcelli.

2:00 PM to 2:30PM

Maria Emília Rodrigues de Oliveira Thais. Pós-Graduação em Ciências Médicas da UFSC. Florianópolis, Brasil.
Theory of Mind in the Epilepsies. <mariaemiliathais@me.com>

2:30 PM to 3:00PM

Claudia Maurer Morelli. Universidade Estadual de Campinas, Campinas, Brasil. From Zebrafish to Epileptic seizures in Patients: The Power of Translation. <cmorelli@unicamp.br>

3:00 PM to 3:30PM

Aline Pansani. Department of Physiological Sciences - Biological Sciences Institute, Universidade Federal de Goiás. Goiás, Brasil. From Breath to Beat: The Cardiorespiratory Factors in SUDEP <alineppansani@gmail.com>

3:30 PM to 4:00PM

COFFEE-BREAK

4:00 PM to 4:30PM

Hana Kubová. Department of Developmental Epileptology, Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic. The behavioural Outcome of Status Epilepticus. Lessons from Laboratory Animals. <kubova@biomed.cas.cz>

4:30 PM to 5:00PM

Maria Elisa Calcagnotto - Universidade Federal do Rio Grande do Sul. Porto Alegre, Brasil. Synaptic and Brain Oscillation Patterns in Misshapen Neuronal Networks. <elisa.calcagnotto@ufrgs.br>

5:00 PM to 6:00PM

GENERAL DISCUSSION

21st SEPTEMBER

8:15AM to 12:15AM

THIRD ROUND TABLE: MORNING SESSION

Channels, Neurons, Glia and Vascular Protagonists of Complex Epileptogenic Networks.

Chair: Prof. Victor R. Santos;
Co-Chair: Vera Cristina Terra.

8:15AM to 8:45AM

Olagide Wagner de Castro. Universidade Federal de Alagoas. Maceió, Brasil. Crack Cocaine and Epilepsy: What We Do Not Know Yet? <olagidewww@gmail.com>

8:45AM to 9:15AM

Patrick Forcelli. Georgetown University, Washington DC, USA. "Basal Ganglia-Brainstem Networks in Epilepsy". <paf22@georgetown.edu>

9:15AM to 9:45AM

Jenny Hsieh. Univ Texas San Antonio, San Antonio, USA. Stem Cell Approaches to Understanding Acquired and Genetic Epilepsies. <jenny.hsieh@utsa.edu>

9:45AM to 10:15AM

COFFEE-BREAK

10:15AM to 10:45AM

Cristina Ruedell Reschke. RCI University of Medicine and Health Sciences, School of Pharmacy and Biomolecular Sciences, Dublin, Ireland. The Molecular Rhythms of Epileptogenesi. <cristinarreschke@rcsi.com>

10:45AM to 11:15AM

Alberto Lazarowski. Faculty of Pharmacy and Biochemistry, University of Buenos Aires. Buenos Aires, Argentina. Ferroptosis in the Epileptic Context and Risk of SUDEP. <alazarowski@gmail.com>

11:15AM to 12:15AM

GENERAL DISCUSSION

12:15AM to 2:00PM

LUNCH-BREAK

2:00PM to 6:00PM

FOURTH ROUND TABLE: AFTERNOON SESSION

Epilepsy and Neuropsychiatric Comorbidities. Challenges for Diagnosis, Treatment, and the Concept of Pharmacoresistance.

Chair: Prof. Luisa Rocha;
Co-Chair: Prof. Alan Talevi.

2:00PM to 2:30PM

Vera Cristina Terra. Comprehensive Care Center for Epilepsy –EPICENTRO, Nossa Senhora das Graças Hospital, Curitiba, Brasil. Pseudoseizures, Seizures and Epilepsies: How Can we Objectively Differentiate them. <v.c.terra@gmail.com>

2:30PM to 3:00PM

Luisa Rocha - Universidad Autónoma de Mexico. Ciudad de Mexico, Mexico. Pharmacoresistance in the Epilepsies: Clues from Animal Models and Resected Human Tissue. <lrocha@cinvestav.mx>

3:00PM to 3:30PM

Alan Talevi. Laboratorio de Investigación y Desarrollo de Bioactivos Universidad de La Plata. La Plata, Argentina. The Underestimated Association Between Drug Resistant Epilepsies and Neuropsychiatric Comorbidities. <atalevi@biol.unlp.edu.ar>

3:30PM to 4:00PM

COFFEE-BREAK

4:00PM to 4:30PM

Idrish Ali. - Monash University. Melbourne, Australia. Neuroinflammation as Biomarker and Preventive Option for Epilepsy and Neurobehavioural Consequences. <idrish.ali@monash.edu>

4:30PM to 5:00PM

Peter A. Tass. Department of Neurosurgery, Stanford University School of Medicine, Stanford, USA. Vibrotactile Fingertip Stimulation for the Treatment of Parkinson’s Disease and Possible Applications to Epilepsy. <ptass@stanford.edu>

5:00PM to 6:00PM

GENERAL DISCUSSION

22nd SEPTEMBER

8:15AM to 12:15AM

FIFTH ROUND TABLE: MORNING SESSION

Neuropathology, Inflammation, Connectomes, Negative and Positive Neuroplasticity.

Chair: Cristina Ruedell Reschke;
Co-Chair: Olagide Wagner de Castro.

8:15AM to 8:45AM

Rossella Di Sapia. Laboratory of Experimental Neurology - Mario Negri Institute for Pharmacological Research. Milano. Italy. Inflammatory Mediators in the Etiopathogenesis of Seizures and their Impact in the Mechanisms of Pharmacoresistance. <rossella.disapia@marionegri.it>

8:45AM to 9:15AM

Sandra Orozco. Medical Research Unit in Neurological Diseases, Specialty Hospital, National Medical Center, Ciudad de Mexico, Mexico. Assessment of Neuroinflammation in Drug - Resistant Epilepsy: The Role of Autoimmunity. <sorozco5@hotmail.com>

9:15AM to 9:45AM

Victor Rodrigues Universidade Federal de Minas Gerais - Brasil. The Treatment of Immature Brain Seizures and Epileptogenesis from the Viewpoint of Cannabinoids. <victorrsantos@gmail.com>

9:45AM to 10:15AM

COFFEE-BREAK

10:15AM to 10:45AM

Maira Licia Foresti - Universidade Federal de São Paulo. São Paulo, Brazil. Modeling of Post-Traumatic Epilepsy and Experimental Research aimed at its Prevention. <mairalicia@yahoo.com.br>

10:45AM to 11:15AM

Efrain Buriticá. Universidad del Valle. Cali, Colombia. On Post-Traumatic Epilepsies and other Drug-Resistant Epilepsies: In the Search for Biomarkers in Surgical Human Brain Tissue. <efrain.buritica@correounivalle.edu.co>

11:15AM to 12:15AM

GENERAL DISCUSSION

12:15AM to 2:00PM

LUNCH-BREAK

2:00PM to 6:00PM

SIXTH ROUND TABLE: AFTERNOON SESSION

Paradigm Shifts towards Integrative Views in the Research of the Epilepsies and Neuropsychiatric Comorbidities.

Chair: Prof. Marcio Flávio Dutra Moraes;
Co-Chair: Hana Kubová.

2:00PM to 2:30PM

Candi LaSarge. Department of Anesthesia. Cincinnati Children's Hospital. University of Cincinnati. Cincinnati, USA. mTOR Hyperactivity Initiates an Epileptogenic Cascade. <candi.lasarge@cchmc.org>

2:30PM to 3:00PM

Ana Carolina Coan. Department of Neurology Universidade de Campinas - UNICAMP. Campinas. Brasil. Mapping the Maze: Navigating the Complex Relationship of Epilepsy, White Matter Integrity, and Neurodevelopmental Impairment. <acoan@unicamp.br>

3:00PM to 3:30PM

David Ahmedt-Aristizabal. Imaging and Computer Vision Group CSIRO Data61. Canberra, Australia. Computer Vision for Understanding Patients’ Behavior: A Focus on Epilepsy and other Motor Disorders. <david.ahmedtaristizabal@data61.csiro.au>

3:30PM to 4:00PM

COFFEE-BREAK

4:00PM to 4:30PM

Marcio F.D. Moraes. University of Minas Gerais - Brazil. Changing a Localizationist Brain Architecture View for One of Temporally Organized Packages. The Concept of Coincidence Detectors instead of Integration-Response and its Impact in the Treatment of the Epilepsies. <marcionnc@gmail.com>

4:30PM to 5:00PM

Norberto Garcia-Cairasco. Ribeirão Preto School of University of São Paulo. Brazil. Challenges to Decipher the Main Intertwined Protagonists of Epileptogenesis and Comorbidities in a Complex Landscape of Semiology, Neuroanatomical Networks and their Neuroplastic Abnormal Activity <ngcairas@usp.br>

5:00PM to 6:00PM

GENERAL DISCUSSION

6:00PM to 6:30PM

FINAL COMMENTARIES

6:30PM to 7:00AM

CLOSING REMARKS

7:00PM to 10:00PM

FAREWELL PARTY

Acknowledgements: To all the past and present members of the Neurophysiology and Experimental Neuroethology Laboratory (LNNE) at the Physiology Department at the Ribeirão Preto Medical School at the University of São Paulo, Brasil, to whom the current International Symposium NEWroscience 2023 is dedicated, because of the 35^th celebration of the foundation of LNNE. As in other opportunities, in addition to the small group of Faculty members involved in the organization of this event, LNNE members, both students and technical staff, are those who compose the various committees responsible for this enormous endeavor. To all the members of the Departments of Physiology, Psychobiology and Neuroscience and Behavioral Science and their corresponding Graduate Programs, respectively, in Physiology, Psychobiology and Neurology/Neuroscience, for their continuous support to the LNNE Academic, Scientific and Outreach (Neuro-Art) activities, over almost four decades. To the Brazilian Research Foundations FAPESP, CNPq, CAPES, FAEPA for their financial support with grants and fellowships. Thanks always to the Liga Brasileira de Epilepsia (LBE), Sociedade Brasileira de Fisiologia (SBFis), Sociedade Brasileira de Neurociências e Comportamento (SBNeC), Federação Brasileira de Sociedades de Biologia Experimental (FESBE), Colegio Colombiano de Neurociencias (COLNE), International Brain Research Organization (IBRO), Dana Foundation for Brain Initiatives – Brain Awareness Week. To Professor Steve C. Schachter, from University of Harvard, Founder and former Editor-in-Chief of Epilepsy & Behavior (E&B) – Elsevier. Thanks to his vision and generosity, we developed the NEWroscience series (every five years) since 2008 (www.sciencedirect.com/journal/epilepsy-and-behavior/vol/14/issue/1/suppl/S1), as a Supplement and in the following every 5 years with the successful volumes NEWroscience 2013 (www.sciencedirect.com/journal/epilepsy-and-behavior/vol/38/suppl/C), 2018 (www.sciencedirect.com/journal/epilepsy-and-behavior/vol/121/part/PB). The current International Symposium NEWroscience 2023 and the associated Special Issue of Epilepsy & Behavior with 30 articles/reviews written by the invited speakers (15 female scientists and 15 male scientists from the 5 continents; details in the program) of the Conference are also supported by Professor Marco Mula from University of London as the current Editor-in-Chief of Epilepsy & Behavior and obviously by Elsevier. This event is a realization of the Science, Arts, Education and Society – ScienArtES – Network from the Institute for Advanced Studies (IEA) at the Campus of Ribeirão Preto at the University of São Paulo. Thanks to the whole team of the IEA who made this event possible and available throughout its site, digital and social media channels. A final thanks to the Ribeirão Preto Law School at the University of São Paulo, in the name of its Director and staff, for allowing us to celebrate this event in its excellent Main Auditorium.